Replacing Animal Research | A better future for animals and humans

2.54 million

scientific procedures were carried out using animals in 2025 in Great Britain.

95%

of all procedures used mice, rats, birds, or fish.

1.3%

of all procedures used specially protected species (cats, dogs, horses, and non-human primates).

We are Replacing Animal Research

We believe in a future where no animal suffers for science. For over 50 years, we’ve championed non-animal research, by funding exciting human-relevant research, collaborating with and educating scientists, and influencing policy to accelerate the shift away from animal testing.

Last year, 2.54 million scientific procedures were carried out on animals in Great Britain. We want to see that number get to zero.

Founded in 1969 by Dorothy Hegarty, we were originally known as FRAME (Fund for the Replacement of Animals in Medical Experiments). Today, we continue her legacy by bridging science, ethics, and innovation.

Join Us

Whether you’re a scientist, a donor, or simply someone who cares, you can be part of the change.

Donate to support non-animal research
Apply for grants if you’re a researcher
Stay informed through our resources, blogs, and impact reports

Together, we can create a better future for animals and humans.

Join our weekly charity lottery from just £1 a week for your chance to win up to £25,000, all while funding humane science that replaces the use of animals in research.

Play our charity lottery

The dedication and determination that Replacing Animal Research has to replace the use of animals in science is inspirational… Their vision ‘no animal suffers for science’ is very poignant to me and I am passionate about being a part of a community that shows the effectiveness of alternative in vitro models compared to animal studies.

Sophie Bateman – 2024 Summer Studentship winner